N-Phthaloylglycine → HCID 59574842, compound

HRID 2092039Notes

Reaction equation

HRID 2092039 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5](Cl)=[CH:6][C:7]=1[CH3:8].[O:10]=[C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[C:13](=[O:20])[N:12]1[CH2:21]C(O)=O>>[CH3:8][C:7]1[C:6]([CH2:21][N:12]2[C:13](=[O:20])[C:14]3[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:11]2=[O:10])=[CH:5][N:4]=[N:3][CH:2]=1

Participants

3

Reactant 2

HCID 20825N-PhthaloylglycineHCID 879233,6-Dichloro-4-methylpyridazine

Product 1

HCID 59574842HCID 59574842, compound

Procedure

Synthesis was carried out in the same manner as in Reference Synthetic Example 54 by using 3,6-dichloro-4-methylpyridazine and 2-(1,3-dioxoisoindolin-2-yl)acetic acid. The obtained crude product was used for the next reaction.

Workup

  1. customSynthesis
  2. customThe obtained crude product
  3. customwas used for the next reaction

Sources & evidence

ORD record
ord-5fd39a7b0d88415f9bbd1ed401e59ebc
Source dataset
uspto-grants-2013_05
Patent number
US08440666B2

Reaction notes

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