Tert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylate → HCID 68770121, compound

HRID 2092196Notes

Reaction equation

HRID 2092196 reaction equation
[CH2:1]1[CH:5]2[CH2:6][NH:7][CH2:8][CH:4]2[CH2:3][N:2]1[C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10].Br[C:17]1[CH:18]=[C:19]([S:23]([C:26]2[CH:27]=[N:28][C:29]3[C:34]([CH:35]=2)=[CH:33][CH:32]=[CH:31][C:30]=3I)(=[O:25])=[O:24])[CH:20]=[CH:21][CH:22]=1>>[C:12]([O:11][C:9]([N:2]1[CH2:3][CH:4]2[CH2:8][N:7]([C:17]3[CH:18]=[C:19]([S:23]([C:26]4[CH:27]=[N:28][C:29]5[C:34]([CH:35]=4)=[CH:33][CH:32]=[CH:31][C:30]=5[N:7]4[CH2:6][CH:5]5[CH2:1][N:2]([C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10])[CH2:3][CH:4]5[CH2:8]4)(=[O:25])=[O:24])[CH:20]=[CH:21][CH:22]=3)[CH2:6][CH:5]2[CH2:1]1)=[O:10])([CH3:15])([CH3:14])[CH3:13]

Participants

3

Reactant 2

HCID 4142526Tert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylateHCID 66853648HCID 66853648, compound

Product 1

HCID 68770121HCID 68770121, compoundYield 12%

Procedure

The title compound was prepared by analogy to the procedure of 1.3, except using tert-butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate and 3-(3-bromophenylsulfonyl)-8-iodoquinoline. 18 mg (12%) of the title compound were obtained as a pale yellow solid

Workup

  1. customThe title compound was prepared by analogy to the procedure of 1.3

Sources & evidence

ORD record
ord-bd6dc63008c1445d9b13b522797fb947
Source dataset
uspto-grants-2013_05
Patent number
US08440694B2

Reaction notes

Loading…