HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate → tert-butyl 5-(3-(3-(trifluoromethyl)phenylsulfonyl)quinolin-8-yl)hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate | HCID 44474550 | — |
| Reactant | 8-Iodo-3-(3-(trifluoromethyl)phenylsulfonyl)quinoline | HCID 67313511 | — |
| Product | tert-butyl 5-(3-(3-(trifluoromethyl)phenylsulfonyl)quinolin-8-yl)hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate | HCID 68728985 | 56% |
Reaction Steps
The title compound was prepared by analogy to the procedure of Example 1.3, except using tert-butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate and 8-iodo-3-(3-(trifluoromethyl)phenylsulfonyl)quinoline. 133 mg (56%) of the title compound were obtained as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440694B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-ebe6b73bde304becaf8cd8c831a9aafa |
| Source note | uspto-grants-2013_05 |