HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl (1s,5r)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate → (1S,5R)-tert-butyl 3-(3-(3-fluorophenylsulfonyl)quinolin-8-yl)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl (1s,5r)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate | HCID 23635291 | — |
| Reactant | 3-(3-Fluorophenylsulfonyl)-8-iodoquinoline | HCID 67314157 | — |
| Product | (1S,5R)-tert-butyl 3-(3-(3-fluorophenylsulfonyl)quinolin-8-yl)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate | HCID 68728715 | — |
Reaction Steps
0.153 g of (1S,5R)-tert-butyl 3-(3-(3-fluorophenylsulfonyl)quinolin-8-yl)-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate were prepared by analogy to the method of Example 25.4 by coupling of 3-(3-fluorophenylsulfonyl)-8-iodoquinoline and (1S,5R)-tert-butyl 3,6-diazabicyclo[3.2.0]heptane-6-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440694B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-e12ec94af4704f19b52f83b8d965e595 |
| Source note | uspto-grants-2013_05 |