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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2092362Generated: November 2, 2026

2-Thiophenemethanol → Carbonic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester thiophen-2-ylmethyl ester

https://huagongshe.com/reaction/2092362

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ThiophenemethanolHCID 69467—
Reactantimidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl esterHCID 59187189—
ProductCarbonic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester thiophen-2-ylmethyl esterHCID 59187160—

Reaction Steps

The desired product was prepared by reacting imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester with 2-hydroxy methyl thiophene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08440690B2
Source datasetuspto-grants-2013_05
ORD IDord-a9e647b2cfa5434b9441f156e754a02c
Source noteuspto-grants-2013_05