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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2092365Generated: October 31, 2026

3-Fluoro-3'-methoxybenzhydrol → Carbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester (3-fluoro-phenyl)-(3-methoxy-phenyl)-methyl ester

https://huagongshe.com/reaction/2092365

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-3'-methoxybenzhydrolHCID 2758989—
Reactantimidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl esterHCID 59187189—
ProductCarbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester (3-fluoro-phenyl)-(3-methoxy-phenyl)-methyl esterHCID 86638969—

Reaction Steps

The desired product was prepared by reacting imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester with (3-fluoro-phenyl)-(3-methoxy-phenyl)-methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08440690B2
Source datasetuspto-grants-2013_05
ORD IDord-53bc6924074a478d8ef490f08a66b8e3
Source noteuspto-grants-2013_05