HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azidotrimethylsilane → {3-Methyl-5-[4'-(2H-tetrazol-5-ylmethyl)-biphenyl-4-yl]-isoxazol-4-yl}-carbamic acid (R)-1-(2-chloro-phenyl)-ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azidotrimethylsilane | HCID 78378 | — |
| Reactant | [5-(4'-Cyanomethyl-biphenyl-4-yl)-3-methyl-isoxazol-4-yl]-carbamic acid (R)-1-(2-chloro-phenyl)-ethyl ester | HCID 46239206 | — |
| Product | {3-Methyl-5-[4'-(2H-tetrazol-5-ylmethyl)-biphenyl-4-yl]-isoxazol-4-yl}-carbamic acid (R)-1-(2-chloro-phenyl)-ethyl ester | HCID 46239101 | — |
Reaction Steps
Prepared as described in Example 45 using [5-(4′-cyanomethyl-biphenyl-4-yl)-3-methyl-isoxazol-4-yl]-carbamic acid (R)-1-(2-chloro-phenyl)-ethyl ester and azidotrimethylsilane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440707B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-5862408f364b48709168ec3cbe34c714 |
| Source note | uspto-grants-2013_05 |