HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 5-Amino-adamantane-2-thiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | (4-Mercapto-adamantan-1-yl)-carbamic acid benzyl ester | HCID 58192789 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 5-Amino-adamantane-2-thiol | HCID 51038894 | — |
Reaction Steps
To 11A (51 mg, 0.16 mmol) was added HBr (33% in HOAc) 2 mL and the mixture was stirred at rt for 2 h. Ether (10 mL×2) was added and the resulting precipitate was collected and dried under vacuum to give the title compound as hydrogen bromide salts (11). LC-MS (ESR): m/z=184 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440720B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-d9a9254f404740de97f81d4d518b0eee |
| Source note | uspto-grants-2013_05 |