6-(Propan-2-yl)pyridin-3-amine → HCID 66577911, compound

HRID 2092659Notes

Reaction equation

HRID 2092659 reaction equation
C(O[C:4]([C:6]1([CH2:13][CH2:14]OC)[CH2:11][CH2:10][CH:9]([OH:12])[CH2:8][CH2:7]1)=[O:5])C.[CH:17]([C:20]1[N:25]=[CH:24][C:23]([NH2:26])=[CH:22][CH:21]=1)([CH3:19])[CH3:18]>>[OH:12][CH:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:5])[N:26]([C:23]3[CH:24]=[N:25][C:20]([CH:17]([CH3:19])[CH3:18])=[CH:21][CH:22]=3)[CH2:14][CH2:13]2)[CH2:11][CH2:10]1

Participants

3

Procedure

The title compound was prepared in analogy to example 1, step 4 from 4-hydroxy-1-(2-methoxy-ethyl)-cyclohexanecarboxylic acid ethyl ester (obtained in example 2, step 3) by treatment with 6-isopropylpyridin-3-amine [CAS Reg. No. 405103-O2-8]. MS (m/e): 289.1 [MH+].

Sources & evidence

ORD record
ord-0ca44d48fe0d457da2bf8a01c0864e4e
Source dataset
uspto-grants-2013_05
Patent number
US08440710B2

Reaction notes

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