HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-bromo-4-(trifluoromethyl)- → 10-(4-Trifluoromethyl-phenyl)-1,4-dioxa-10-aza-dispiro[4.2.4.2]tetradecan-9-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-bromo-4-(trifluoromethyl)- | HCID 67872 | — |
| Reactant | 1,4-Dioxa-10-azadispiro[4.2.4.2]tetradecan-9-one | HCID 58230108 | — |
| Product | 10-(4-Trifluoromethyl-phenyl)-1,4-dioxa-10-aza-dispiro[4.2.4.2]tetradecan-9-one | HCID 58229993 | — |
Reaction Steps
The title compound was prepared in analogy to example 133, step 4 from 1,4-dioxa-10-aza-dispiro[4.2.4.2]tetradecan-9-one (described in example 133 step 3) and 1-bromo-4-(trifluoromethyl)benzene as white crystalline solid. MS (m/e): 356.146 [(M-H2O)H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440710B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-0b162c39f66d4d0eb0654b6782fb7259 |
| Source note | uspto-grants-2013_05 |