HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → N-(4-bromo-2-nitrophenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4'-Bromoacetanilide | HCID 7683 | — |
| Product | N-(4-bromo-2-nitrophenyl)acetamide | HCID 136690 | 95% |
Reaction Steps
N-(4-Bromophenyl)acetamide obtained in step I above was nitrated using nitric acid (1.2 eq)+H2SO4 (1.0 eq) at 0 to 5° C. for 2 hrs. After the completion of the reaction, reaction mixture was added to ice and pH was adjusted to 8, extracted with dichloromethane, which was evaporated to dryness to obtain N-(4-bromo-2-nitrophenyl)acetamide. (Yield=95%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440830B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-1660a4d72c624b3fb70ce9e325c62255 |
| Source note | uspto-grants-2013_05 |