huagongshe.com
HRID2093091

反应详情

EQUATION

反应方程式

HRID 2093091 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：COC(=O)c1cc2c(s1)CCN(C(=O)OC(C)(C)C)C2
HCID66523223

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCc2sc(C(=O)O)cc2C1
HCID17750399

5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxylic acid

C13H17NO4S

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A solution of 5-tert-butyl 2-methyl 6,7-dihydrothieno[3,2-c]pyridine-2,5(4H)-dicarboxylate (1 eq) obtained in step VII and NaOH (1.5 eq). was refluxed in ethanol for 2 h Reaction mixture was concentrated under reduced pressure and neutralized to get 5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-2-carboxylic acid.

WORKUP

后处理

  1. customReaction mixture
  2. concentrationwas concentrated under reduced pressure