Water → 2-Bromo-3-hexylthiophene

Participants

Reaction Steps

60 g of 3-n-hexylthiophene was dissolved in 400 ml of dimethylformamide, and to this, 50 g of N-bromosuccinimide was added. The resulting solution was stirred at room temperature for 4 hours under a nitrogen atmosphere. 200 ml of water and 200 ml of hexane were added to the resulting solution to separate the organic layer. The organic layer was washed with 200 ml of water and dried over magnesium sulfate, and then the solvent was distilled off under reduced pressure with a rotary evaporator to obtain 60 g of 2-bromo-3-n-hexylthiophene.

Provenance & Evidence