Hexane → HCID 57704765, compound

Participants

Reaction Steps

To a solution of the title compound from Step B (30 mg, 0.035 mmol) in dioxane (2 ml) at room temperature, an aqueous solution of LiOH.H2O (7.36 mg, 0.175 mmol) was added. The mixture was stirred at room temperature for overnight. TLC (EtOAc:hexane/2:8) showed no starting material. The solvent was removed. 1N HCl (1 ml) was added. The mixture was extracted with methylene chloride (3×10 ml). The combined methylene chloride layers were dried over sodium sulfate. The title compound was obtained by preparative reverse phase HPLC as a colorless solid.

Provenance & Evidence