Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | {3,5-Bis[(prop-2-yn-1-yl)oxy]phenyl}methanol | HCID 15203944 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Product | HCID 59806471 | HCID 59806471 | 96% |
Reaction Steps
3,5-Dipropargyloxybenzyl alcohol (I) (6.3 g, 0.029 mol) was stirred in acetic anhydride (7 mL, 0.07 mol). Concentrated sulfuric acid (2 drops) was added and the solution was stirred (90-100° C.) for 3 hours. The solution was then poured into ice water, neutralized with a saturated sodium carbonate solution and after the reaction was worked up, the product was purified using silica in a sintered glass funnel and the solvents were removed leaving a yellow oil, which solidified upon standing, 7.2 g in 96% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08444953B2 |
|---|
| Source dataset | uspto-grants-2013_05 |
|---|
| ORD ID | ord-553441f12cb34e3fa160d6f600c488ad |
|---|
| Source note | uspto-grants-2013_05 |
|---|
