Magnesium;2-carboxyphenolate;2-hydroxybenzoic acid;2-hydroxyethyl(trimethyl)azanium → Choline

HRID 2093306Notes

Reaction equation

HRID 2093306 reaction equation
[CH3:1][N+:2]([CH2:5][CH2:6][OH:7])([CH3:4])[CH3:3].[CH:8]1[CH:13]=[C:12]([C:14]([OH:16])=[O:15])[C:11]([OH:17])=[CH:10][CH:9]=1.C1C=C(C(O)=O)C([O-])=CC=1.[Mg+2].C([O-])(=O)C1C(=CC=CC=1)O.C([O-])(=O)C1C(=CC=CC=1)O.C([O-])(=O)C1C(=CC=CC=1)O.[Mg+2].OCC[N+](C)(C)C>O>[OH:7][CH2:6][CH2:5][N+:2]([CH3:4])([CH3:3])[CH3:1].[C:14]([O-:16])(=[O:15])[C:12]1[C:11](=[CH:10][CH:9]=[CH:8][CH:13]=1)[OH:17]

Participants

5

Reactant 2

HCID 54697707Magnesium;2-carboxyphenolate;2-hydroxybenzoic acid;2-hydroxyethyl(trimethyl)azanium2×HCID 178483604HCID 178483604, compound2×

Product 2

HCID 305CholineHCID 178524311Salicylate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

Trilisate (choline magnesium trisalicylate) is freely soluble in water. The absolute structure of choline magnesium trisalicylate is not known at this time. Choline magnesium trisalicylate has a molecular formula of C26H29O10NMg, and a molecular weight of 539.8. When dissolved in water, trilisate appears to form 5 ions (one choline ion, one magnesium ion, and three salicylate ions).

Sources & evidence

ORD record
ord-2ed425b32d5542e4982d69c6a79ed8cb
Source dataset
uspto-grants-2013_05
Patent number
US08445467B2

Reaction notes

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