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HRID2093387

反应详情

EQUATION

反应方程式

HRID 2093387 的结构方程式

REACTANTS

反应物

2
结构：Cc1nc(N)ncc1B1OC(C)(C)C(C)(C)O1
HCID52987906

4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine

C11H18BN3O2

结构：CC(=O)OCCn1c(C(C)(C)O)nc2c(N3CCOCC3)nc(Cl)nc21
HCID58015224

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(N)ncc1-c1nc(N2CCOCC2)c2nc(C(C)(C)O)n(CCO)c2n1
HCID44544943

未命名化合物

PROCEDURE

实验过程

2-(2-Chloro-8-(2-hydroxypropan-2-yl)-6-morpholino-9H-purin-9-yl)ethyl acetate (300 mg) was treated with 4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine via General Procedure A and was purified via reverse phase HPLC to give 107 mg of 102 as a white solid. MS (Q1) 415.2 (M)+

WORKUP

后处理

  1. customwas purified via reverse phase HPLC