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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2093641Generated: October 30, 2026

Methyl 4-(chlorocarbonyl)benzoate → Methyl 4-[5-cyano-7-(methylthio)-1,3-benzoxazol-2-yl]benzoate

https://huagongshe.com/reaction/2093641

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(chlorocarbonyl)benzoateHCID 81850—
Reactant3-Amino-4-hydroxy-5-(methylthio)benzonitrileHCID 68726375—
ReactantHCID 86643502HCID 86643502—
ProductMethyl 4-[5-cyano-7-(methylthio)-1,3-benzoxazol-2-yl]benzoateHCID 68784684—

Reaction Steps

The title compound was prepared from 3-amino-4-hydroxy-5-(methylthio)benzonitrile and methyl 4-(chlorocarbonyl)benzoate by a procedure analogous to that described in INTERMEDIATE 1, Step C. Mass spectrum (ESI) 325.0 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445480B2
Source datasetuspto-grants-2013_05
ORD IDord-c18e3fb8370d4072847f753c14e66798
Source noteuspto-grants-2013_05