4-(5-Cyano-7-isopropylbenzo[d]oxazol-2-yl)benzoic acid → 4-[5-Cyano-7-(methylthio)-1,3-benzoxazol-2-yl]benzoic acid

HRID 2093642Notes

Reaction equation

HRID 2093642 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([S:22][CH3:23])[C:6]2[O:10][C:9]([C:11]3[CH:20]=[CH:19][C:14]([C:15]([O:17]C)=[O:16])=[CH:13][CH:12]=3)=[N:8][C:7]=2[CH:21]=1)#[N:2].C(C1C=C(C(C)C)C2OC(C3C=CC(C(O)=O)=CC=3)=NC=2C=1)#N>>[C:1]([C:3]1[CH:4]=[C:5]([S:22][CH3:23])[C:6]2[O:10][C:9]([C:11]3[CH:20]=[CH:19][C:14]([C:15]([OH:17])=[O:16])=[CH:13][CH:12]=3)=[N:8][C:7]=2[CH:21]=1)#[N:2]

Participants

3

Reactant 2

HCID 573699454-(5-Cyano-7-isopropylbenzo[d]oxazol-2-yl)benzoic acidHCID 68784684Methyl 4-[5-cyano-7-(methylthio)-1,3-benzoxazol-2-yl]benzoate

Product 1

HCID 687460974-[5-Cyano-7-(methylthio)-1,3-benzoxazol-2-yl]benzoic acid

Procedure

The title compound was prepared from methyl 4-[5-cyano-7-(methylthio)-1,3-benzoxazol-2-yl]benzoate by a procedure analogous to that described in INTERMEDIATE 2, Step C. Mass spectrum (ESI) 311.0 (M+1).

Sources & evidence

ORD record
ord-3ed2aee2476c4f14815e16e9b863a3c9
Source dataset
uspto-grants-2013_05
Patent number
US08445480B2

Reaction notes

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