HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobenzoyl chloride → Methyl 2-(4-bromophenyl)-5-cyano-1,3-benzoxazole-7-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobenzoyl chloride | HCID 68515 | — |
| Reactant | Methyl 3-amino-5-cyano-2-hydroxybenzoate | HCID 68724812 | — |
| Reactant | HCID 86643502 | HCID 86643502 | — |
| Product | Methyl 2-(4-bromophenyl)-5-cyano-1,3-benzoxazole-7-carboxylate | HCID 68789129 | — |
Reaction Steps
The title compound was prepared from 4-bromobenzoyl chloride and methyl 3-amino-5-cyano-2-hydroxybenzoate (INTERMEDIATE 26) by a procedure analogous to that described in INTERMEDIATE 1, Step C. Mass spectrum (ESI) 358.9 (M+3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445480B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-52cd078c1beb4f54a57d416da24bea7e |
| Source note | uspto-grants-2013_05 |