HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → (R)-8-cyclopentyl-7-ethyl-2-hydrazinyl-5-methyl-7,8-dihydropteridin-6(5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | (R)-2-Chloro-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5H)-one | HCID 24820413 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (R)-8-cyclopentyl-7-ethyl-2-hydrazinyl-5-methyl-7,8-dihydropteridin-6(5H)-one | HCID 58405330 | — |
Reaction Steps
Intermediate B and hydrazine (6 equivalents) in ethanol was heated in a microwave for 1 h at 120° C. The solvent was removed to give Intermediate B-2. This material was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445503B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-e6ded0533f5b4b009a34774c7a632a33 |
| Source note | uspto-grants-2013_05 |