HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2093673Generated: October 26, 2026
Potassium Carbonate → 2-(4-(methylthio)phenyl)-1H-imidazole
https://huagongshe.com/reaction/2093673
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(4-(methylthio)phenyl)-4,5-dihydro-1H-imidazole | HCID 44269106 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-(4-(methylthio)phenyl)-1H-imidazole | HCID 22167367 | — |
Reaction Steps
To a solution of 2-(4-(methylthio)phenyl)-4,5-dihydro-1H-imidazole (2-Im-1, 9.6 g, 1.0 eq) in 100 mL of DMSO, DIB (1.1 eq) and K2CO3 (1.1 eq) were added. The mixture was heated to 70° C. overnight, then extracted with EtOAc and the organic layer was concentrated to provide 2-(4-(methylthio)phenyl)-1H-imidazole (compound 3-Im-1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08445503B2 |
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| Source dataset | uspto-grants-2013_05 |
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| ORD ID | ord-11c8d9ac71ae4dca8c4aedb2a07418fe |
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| Source note | uspto-grants-2013_05 |
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