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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2093746Generated: October 31, 2026

Trifluoroacetic acid → HCID 67074718, compound

https://huagongshe.com/reaction/2093746

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67073864HCID 67073864—
SolventDichloromethaneHCID 6344—
ProductHCID 67074718HCID 6707471895.1%

Reaction Steps

To a suspension of tert-butyl 4-(4-(1-(ethoxycarbonyl)cyclopropylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-ylamino)benzoate (1.6 g) in dichloromethane (15 mL) was added TFA (4.96 mL). The mixture was stirred at r.t. for 16 hours. All solvents were removed under vacuum to give product 4-(4-(1-(ethoxycarbonyl)cyclopropylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-ylamino)benzoic acid (1.35 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445490B2
Source datasetuspto-grants-2013_05
ORD IDord-a53df4178d574b609eef03b603475385
Source noteuspto-grants-2013_05