反应详情

To a solution of tert-butyl-4-(4-aminonaphthalen-1-yl)-5,6-dihydropyridine-1(2H)-carboxylate in 50 mL of MeOH was added 10 wt % Pd—C (100 mg). The reaction was degassed to remove air and stirred under 1 atm. H2 until the starting material is consumed. The Pd—C was removed by filtration and the resulting solution was concentrated in vacuo to afford tert-butyl-4-(4-aminonaphthalen-1-yl)piperidine-1-carboxylate.

1. customThe reaction was degassed
2. customto remove air
3. customH2 until the starting material is consumed
4. customThe Pd—C was removed by filtration
5. concentrationthe resulting solution was concentrated in vacuo