HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-1-Boc-piperidine → 4-{[4-(2-Cyclopropylmethoxy-5-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carbonyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-1-Boc-piperidine | HCID 1268291 | — |
| Reactant | 4-(2-cyclopropylmethoxy-5-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid | HCID 66867178 | — |
| Product | 4-{[4-(2-Cyclopropylmethoxy-5-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carbonyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester | HCID 66867513 | — |
Reaction Steps
Starting from 4-(2-cyclopropylmethoxy-5-methoxy-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example A75) and 4-amino-piperidine-1-carboxylic acid tert-butyl ester the title compound is obtained as colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445501B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-50bb629e3ad448b08c131b7027f831fc |
| Source note | uspto-grants-2013_05 |