Methoxyacetyl chloride → AKOS BBV-015832

HRID 2093920Notes

Reaction equation

C(OC([C:8]1([NH2:14])[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=O)(C)(C)C.[CH3:15][O:16][CH2:17][C:18](Cl)=[O:19]>>[NH2:14][CH:8]1[CH2:9][CH2:10][N:11]([C:18](=[O:19])[CH2:17][O:16][CH3:15])[CH2:12][CH2:13]1

Participants

Reactant 2

HCID 96623Methoxyacetyl chloride

HCID 66867394HCID 66867394, compound

Product 1

HCID 16777912AKOS BBV-015832

Procedure

Starting from 4-amino-piperidine-4-carboxylic acid tert-butyl ester and methoxy-acetyl chloride the title compound is obtained as slightly brown oil.

Sources & evidence

ORD record: ord-5f35fdd132614e36991080ea12be4918
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08445501B2

Reaction notes

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