HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic-formic anhydride → 4-(5-Cyclopropylmethoxy-benzo[1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ((S)-1-formyl-pyrrolidin-3-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic-formic anhydride | HCID 75269 | — |
| Reactant | HCID 66867673 | HCID 66867673 | — |
| Product | 4-(5-Cyclopropylmethoxy-benzo[1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ((S)-1-formyl-pyrrolidin-3-yl)-amide | HCID 44206283 | — |
Reaction Steps
Starting from 4-(5-Cyclopropylmethoxy-benzo[1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (S)-pyrrolidin-3-ylamide hydrochloride (example A143) and acetic formic anhydride the title compound is obtained as colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445501B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-31c3b498e23048abb8315d9b93ea1b54 |
| Source note | uspto-grants-2013_05 |