HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S)-2-Chloro-1-methyl-2-oxoethyl acetate → 4-(5-Cyclopropylmethoxy-benzo[1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid [(S)-1-((S)-2-hydroxy-propanoyl)-pyrrolidin-3-yl]amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S)-2-Chloro-1-methyl-2-oxoethyl acetate | HCID 11094804 | — |
| Reactant | HCID 66867673 | HCID 66867673 | — |
| Product | 4-(5-Cyclopropylmethoxy-benzo[1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid [(S)-1-((S)-2-hydroxy-propanoyl)-pyrrolidin-3-yl]amide | HCID 66867425 | — |
Reaction Steps
Starting from 4-(5-cyclopropylmethoxy-benzo[1,3]dioxol-4-yl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (S)-pyrrolidin-3-ylamide hydrochloride (example A143) and acetic acid (S)-1-chlorocarbonyl-ethyl ester the title compound is obtained as colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445501B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-bcfb957f57054e6c9836ecd336f480ad |
| Source note | uspto-grants-2013_05 |