HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Fluoro-3-methylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Fluoro-3-methylbenzoic acid | HCID 242828 | — |
| Product | 4-Fluoro-3-methylbenzoyl chloride | HCID 2774589 | — |
Reaction Steps
14.00 g (90.8 mmol) 4-fluoro-3-methyl-benzoic acid are refluxed for 1 hour together with 50 ml of thionyl chloride and then evaporated down i. vac. The residue is further reacted without any more purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445525B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-dd2919e8bfa24658a838893439cd1c6b |
| Source note | uspto-grants-2013_05 |