Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094324Generated: November 2, 2026

Tetrahydrofuran → Ethyl 4-[(2-chloro-ethoxy)-acetyl-amino]-3-fluoro-benzoate

https://huagongshe.com/reaction/2094324

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2-(2-Chloroethoxy)acetyl chlorideHCID 19048420—
ReactantEthyl 4-Amino-3-fluorobenzoateHCID 20536493—
ProductEthyl 4-[(2-chloro-ethoxy)-acetyl-amino]-3-fluoro-benzoateHCID 86600579—

Reaction Steps

Prepared analogously to Example 46a from (2-chloro-ethoxy)-acetylchloride and ethyl 4-amino-3-fluoro-benzoate with TEA in THF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445525B2
Source datasetuspto-grants-2013_05
ORD IDord-9f488f706a2e442898c36d1c667b98e4
Source noteuspto-grants-2013_05