HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 3-Fluoro-4-(morpholin-3-on-4-yl)benzoic acid-chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(2-Carboxymethoxy-ethylamino)-3-fluoro-benzoic acid | HCID 66731590 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Fluoro-4-(morpholin-3-on-4-yl)benzoic acid-chloride | HCID 86069379 | — |
Reaction Steps
Prepared analogously to Example 41c from 4-(2-carboxymethoxy-ethylamino)-3-fluoro-benzoic acid and thionylchloride in dichloromethane with DMF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445525B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-4b694774062e463880b0c33f18dafce7 |
| Source note | uspto-grants-2013_05 |