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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094335Generated: November 2, 2026

Trifluoroacetic acid → Ethyl 3-chloro-4-[2-(hydroxycarbonylmethoxy)-1-methyl-ethylamino]-benzoate

https://huagongshe.com/reaction/2094335

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantEthyl 4-[2-(tert.-butoxycarbonyl-methoxy)-1-methyl-ethylamino]-3-chlorobenzoateHCID 67049365—
SolventDichloromethaneHCID 6344—
ProductEthyl 3-chloro-4-[2-(hydroxycarbonylmethoxy)-1-methyl-ethylamino]-benzoateHCID 67048486—

Reaction Steps

Prepared analogously to Example 1g from ethyl 4-[2-(tert.-butoxycarbonyl-methoxy)-1-methyl-ethylamino]-3-chloro-benzoate and trifluoroacetic acid in dichloromethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445525B2
Source datasetuspto-grants-2013_05
ORD IDord-aee4a63809844af5ac923adffe0cdcbf
Source noteuspto-grants-2013_05