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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094337Generated: October 31, 2026

Lithium Hydroxide → 3-Chloro-4-(5-methyl-morpholin-3-on-4-yl)-benzoic acid

https://huagongshe.com/reaction/2094337

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantEthyl 3-chloro-4-(5-methyl-morpholin-3-on-4-yl)-benzoateHCID 67049237—
SolventWaterHCID 962—
SolventTetrahydrofuranHCID 8028—
Product3-Chloro-4-(5-methyl-morpholin-3-on-4-yl)-benzoic acidHCID 67048505—

Reaction Steps

Prepared analogously to Example 31b from ethyl 3-chloro-4-(5-methyl-morpholin-3-on-4-yl)-benzoate with lithium hydroxide in THF and water.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445525B2
Source datasetuspto-grants-2013_05
ORD IDord-50d89b352c004ccebb8f7ae5e892e15e
Source noteuspto-grants-2013_05