HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitro-4-(trifluoromethoxy)phenol → 2-Amino-4-(trifluoromethoxy)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitro-4-(trifluoromethoxy)phenol | HCID 2775775 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Amino-4-(trifluoromethoxy)phenol | HCID 2737729 | 100% |
Reaction Steps
A mixture of 4.53 g of 4-trifluoromethoxy-2-nitrophenol, 35 ml of ethyl acetate and 1.0 g of 5% palladium on carbon was stirred under about one atmosphere of hydrogen at room temperature for 1.7 hours. The mixture was filtered through Celite™. The filtrate was concentrated under reduced pressure to give 3.92 g of 2-amino-4-trifluoromethoxy phenol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445522B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-b5062ff760474de98fe46cbf6d4cf481 |
| Source note | uspto-grants-2013_05 |