HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isocyanatopyridine → N-[4-(4,6-Di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]-N′-3-pyridinylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isocyanatopyridine | HCID 2760493 | — |
| Reactant | 4-(4,6-Dimorpholino-1,3,5-triazin-2-yl)aniline | HCID 45379087 | — |
| Product | N-[4-(4,6-Di-4-morpholinyl-1,3,5-triazin-2-yl)phenyl]-N′-3-pyridinylurea | HCID 44513885 | — |
Reaction Steps
Starting from 4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)aniline (0.08 g 0.23 mmoles) and 3-pyridyl isocyanate (30 mg, 0.25 mmoles) the title compound was isolated as a white solid. The product was purified by Silica gel column chromatography by eluting it with 10% MeOH: ethyl acetate. Yield; 60 mg (56%); (M+H)=463.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445486B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-7aa7c24df76640299056d3ec10e242d6 |
| Source note | uspto-grants-2013_05 |