HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isocyanatopyridine → 1-{4-[4-morpholin-4-yl-6-(tetrahydro-2H-pyran-4-yloxy)-1,3,5-triazin-2-yl]phenyl}-3-pyridin-3-ylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isocyanatopyridine | HCID 2760493 | — |
| Reactant | 4-[4-morpholin-4-yl-6-(tetrahydro-2H-pyran-4-yloxy)-1,3,5-triazin-2-yl]aniline | HCID 67021802 | — |
| Product | 1-{4-[4-morpholin-4-yl-6-(tetrahydro-2H-pyran-4-yloxy)-1,3,5-triazin-2-yl]phenyl}-3-pyridin-3-ylurea | HCID 44515699 | — |
Reaction Steps
1-{4-[4-morpholin-4-yl-6-(tetrahydro-2H-pyran-4-yloxy)-1,3,5-triazin-2-yl]phenyl}-3-pyridin-3-ylurea was prepared by reacting the 4-[4-morpholin-4-yl-6-(tetrahydro-2H-pyran-4-yloxy)-1,3,5-triazin-2-yl]aniline and the corresponding 3-pyridylisocyanate. Product was purified by Gilson, HPLC. MS (ESI) m/z 477.53.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445486B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-7693417f66d84bfba7dd265d2c1b9434 |
| Source note | uspto-grants-2013_05 |