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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094696Generated: November 1, 2026

2-(4-Methoxy-3-nitro-benzoylamino)-indane-2-carboxylic acid methyl ester → HCID 67076603, compound

https://huagongshe.com/reaction/2094696

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Methoxy-3-nitro-benzoylamino)-indane-2-carboxylic acid methyl esterHCID 67076671—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 67076603HCID 6707660396.2%

Reaction Steps

The compound of step 1 (0.43 g, 1.16 mmol) was dissolved in methanol (30 ml), 10% palladium on charcoal (200 mg) was added, and the flask flushed with argon. A balloon filled with hydrogen was connected, and the mixture was stirred at room temperature overnight. The balloon was removed, the flask flushed with argon, the catalyst filtered off over Celite, and the filtrate was evaporated in vacuo to give 0.38 g of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445530B2
Source datasetuspto-grants-2013_05
ORD IDord-cb255396367c4f48b3aa52d3a78face1
Source noteuspto-grants-2013_05