反应详情

10 mg of the compound of example 171 were dissolved in DCM and treated with 200 μl of a 1 M solution of boron tribromide in DCM for 5 h. A 2 M solution of sodium carbonate was added, and the mixture was evaporated in vacuo. The product was purified by preparative RP HPLC (water/ACN gradient).

1. customthe mixture was evaporated in vacuo
2. customThe product was purified by preparative RP HPLC (water/ACN gradient)