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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094728Generated: October 30, 2026

methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochloride → HCID 67076726, compound

https://huagongshe.com/reaction/2094728

Reaction equation

Participants

RoleNameHCIDCharge
Reactantmethyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate hydrochlorideHCID 45074056—
ReactantMethyl 5-bromo-6-methoxypyridine-3-carboxylateHCID 46311221—
ProductHCID 67076726HCID 67076726—

Reaction Steps

5-Bromo-6-methoxy-nicotinic acid methyl ester (W. J. Thompson and J. Gaudino, J. Org. Chem. 49 (1984), 5237-5243) (2.00 g, 8.13 mmol) was hydrolyzed in analogy to example 2. The obtained acid was reacted with 2-amino-indane-2-carboxylic acid methyl ester hydrochloride in analogy to step 2 of example 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445530B2
Source datasetuspto-grants-2013_05
ORD IDord-2f54c33624b443e7a6f13a351284649c
Source noteuspto-grants-2013_05