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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094743Generated: November 2, 2026

Methyl 2-amino-2,3-dihydro-1H-indene-2-carboxylate → 2-[3-Methoxy-4-(2-m-tolyl-ethoxy)-benzoylamino]-indane-2-carboxylic acid

https://huagongshe.com/reaction/2094743

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-2,3-dihydro-1H-indene-2-carboxylateHCID 45074057—
ReactantHCID 67076777HCID 67076777—
Product2-[3-Methoxy-4-(2-m-tolyl-ethoxy)-benzoylamino]-indane-2-carboxylic acidHCID 67076688—

Reaction Steps

The compound of step 3 was hydrolyzed in analogy to example 2, the obtained carboxylic acid reacted with 2-amino-indane-2-carboxylic acid methyl ester in analogy to step 1 of example 15, and the obtained ester hydrolyzed in analogy to example 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445530B2
Source datasetuspto-grants-2013_05
ORD IDord-42c8f932f13f46d4979d6bb2205ad1df
Source noteuspto-grants-2013_05