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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094839Generated: October 30, 2026

Methyl iodide → 5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]2-methylsulfanyl-thiazol-4-one

https://huagongshe.com/reaction/2094839

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-thioxo-thiazolidin-4-oneHCID 86654539—
Product5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]2-methylsulfanyl-thiazol-4-oneHCID 86654543—

Reaction Steps

5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-thioxo-thiazolidin-4-one and iodomethane following General Procedure B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445690B2
Source datasetuspto-grants-2013_05
ORD IDord-b115356d089b4978a62894136b464457
Source noteuspto-grants-2013_05