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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094842Generated: October 26, 2026

Rhodanine → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-thioxo-thiazolidin-4-one

https://huagongshe.com/reaction/2094842

Reaction equation

Participants

RoleNameHCIDCharge
ReactantRhodanineHCID 1201546—
Reactant1H-Indazole-5-carboxaldehydeHCID 21250644—
Reactant1-(4-chloro-2-(trifluoromethyl)benzyl)-1H-indazole-5-carbaldehydeHCID 86654547—
Product5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-thioxo-thiazolidin-4-oneHCID 86656521—

Reaction Steps

5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-thioxo-thiazolidin-4-one was prepared from 1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde was prepared from 1H-indazole-5-carbaldehyde and 2-thioxo-thiazolidin-4-one following General Procedure B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445690B2
Source datasetuspto-grants-2013_05
ORD IDord-844b01917e3b4134bfb1f61e1948d140
Source noteuspto-grants-2013_05