2,5-Dimethoxybenzoic acid → HCID 57422268, compound

HRID 2094860Notes

Reaction equation

HRID 2094860 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[CH:8][C:4]=1[C:5]([OH:7])=O.Cl.[CH3:15][C:16]1[C:20]([CH2:21][N:22]2[CH:26]=[C:25]([NH2:27])[CH:24]=[N:23]2)=[C:19]([CH3:28])[O:18][N:17]=1>>[CH3:15][C:16]1[C:20]([CH2:21][N:22]2[CH:26]=[C:25]([NH:27][C:5](=[O:7])[C:4]3[CH:8]=[C:9]([O:12][CH3:13])[CH:10]=[CH:11][C:3]=3[O:2][CH3:1])[CH:24]=[N:23]2)=[C:19]([CH3:28])[O:18][N:17]=1

Participants

3

Reactant 2

HCID 760272,5-Dimethoxybenzoic acidHCID 574222641-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride

Product 1

HCID 57422268HCID 57422268, compoundYield 13%

Procedure

Prepared as in Example 4-8 from 2,5-dimethoxybenzoic acid and 1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride (Example 4-1a). Yield 13%. MS M+H calculated 357.5, found 357.3.

Sources & evidence

ORD record
ord-00f2aaf23cea40a8abfd67a589473f4b
Source dataset
uspto-grants-2013_05
Patent number
US08445692B2

Reaction notes

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