Pyrrole-2-Carboxylic Acid → HCID 57422271, compound

HRID 2094864Notes

Reaction equation

HRID 2094864 reaction equation
[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([OH:8])=O.Cl.[CH3:10][C:11]1[C:15]([CH2:16][N:17]2[CH:21]=[C:20]([NH2:22])[CH:19]=[N:18]2)=[C:14]([CH3:23])[O:13][N:12]=1>>[CH3:10][C:11]1[C:15]([CH2:16][N:17]2[CH:21]=[C:20]([NH:22][C:6]([C:2]3[NH:1][CH:5]=[CH:4][CH:3]=3)=[O:8])[CH:19]=[N:18]2)=[C:14]([CH3:23])[O:13][N:12]=1

Participants

3

Reactant 2

HCID 12473Pyrrole-2-Carboxylic AcidHCID 574222641-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride

Product 1

HCID 57422271HCID 57422271, compoundYield 18%

Procedure

Prepared as in Example 4-8 from 1H-pyrrole-2-carboxylic acid and 1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride (Example 4-1a). Yield 18%. MS M+H calculated 286.6, found 286.3.

Sources & evidence

ORD record
ord-32fdc78f10964577a064e1ff54649558
Source dataset
uspto-grants-2013_05
Patent number
US08445692B2

Reaction notes

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