Cyclohexaneacetic acid → HCID 57422272, compound

HRID 2094865Notes

Reaction equation

HRID 2094865 reaction equation
[CH:1]1([CH2:7][C:8]([OH:10])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.[CH3:12][C:13]1[C:17]([CH2:18][N:19]2[CH:23]=[C:22]([NH2:24])[CH:21]=[N:20]2)=[C:16]([CH3:25])[O:15][N:14]=1>>[CH:1]1([CH2:7][C:8]([NH:24][C:22]2[CH:21]=[N:20][N:19]([CH2:18][C:17]3[C:13]([CH3:12])=[N:14][O:15][C:16]=3[CH3:25])[CH:23]=2)=[O:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 21363Cyclohexaneacetic acidHCID 574222641-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride

Product 1

HCID 57422272HCID 57422272, compoundYield 17%

Procedure

Prepared as in Example 4-8 from 2-cyclohexylacetic acid and 1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride (Example 4-1a). Yield 17%. MS M+H calculated 317.6, found 317.4.

Sources & evidence

ORD record
ord-d04cba4cfbd24599ad682f28d994f8f6
Source dataset
uspto-grants-2013_05
Patent number
US08445692B2

Reaction notes

Loading…