HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzylamine → HCID 57422469, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzylamine | HCID 21156 | — |
| Reactant | HCID 57422464 | HCID 57422464 | — |
| Product | HCID 57422469 | HCID 57422469 | 50% |
Reaction Steps
Prepared as in Example 10-48 from 3-(1-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-2,5-dioxoimidazolidin-4-yl)acetic acid (example 10-44) and (3-methoxyphenyl)methanamine. Yield: 50%. LC/MS; expected 453; found 453.1 The title compound was shown to inhibit hT2R08 bitter receptor and had an IC50 of 1.7 μM.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445692B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-c5ba6262b4524384ab10cffd94424b66 |
| Source note | uspto-grants-2013_05 |