Ethyl 1-aminocyclopentane-1-carboxylate--hydrogen chloride (1/1) → HCID 59524409, compound

HRID 2095046Notes

Reaction equation

HRID 2095046 reaction equation
[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH:12]=O)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].Cl.[NH2:18][C:19]1([C:24]([O:26][CH2:27][CH3:28])=[O:25])[CH2:23][CH2:22][CH2:21][CH2:20]1>>[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH2:12][NH:18][C:19]1([C:24]([O:26][CH2:27][CH3:28])=[O:25])[CH2:23][CH2:22][CH2:21][CH2:20]1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 3028134Ethyl 1-aminocyclopentane-1-carboxylate--hydrogen chloride (1/1)HCID 112071113-(t-Butyldimethylsilyloxy)benzaldehyde

Product 1

HCID 59524409HCID 59524409, compoundYield 77%

Procedure

Prepared as in Example 1b-JF from 3-(tert-butyldimethylsilyloxy)benzaldehyde (Example 12-1c) and ethyl 1-aminocyclopentanecarboxylate hydrochloride. Yield 77%, a colorless liquid. MS 378 (MH+).

Sources & evidence

ORD record
ord-5721b19a0b1548ce8ba8663f4f2c0ccd
Source dataset
uspto-grants-2013_05
Patent number
US08445692B2

Reaction notes

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