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HRID2095065

反应详情

EQUATION

反应方程式

HRID 2095065 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(CCBr)cc1
HCID84427

1-(2-Bromoethyl)-4-methoxybenzene

C9H11BrO

结构：Cc1noc(C)c1Cn1cc(N2C(=O)NC(C)(C)C2=O)cn1
HCID59524388

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(CCN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1
HCID53373640

未命名化合物

PROCEDURE

实验过程

Prepared as in Example 12-16 from 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-5,5-dimethylimidazolidine-2,4-dione (Example 12-16a) and 1-(2-bromoethyl)-4-methoxybenzene. MS 438 (MH+). The title compound was shown to inhibit hT2R08 bitter receptor and had an IC50 of 0.12 μM.