Dimethyl Sulfoxide → 3-Chloro-2-p-methoxyphenoxy-5-trifluoromethylpyridine

HRID 209510Notes

Reaction equation

HRID 209510 reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([OH:9])[cH:7][cH:8]1.[CH3:30][S:31](=[O:32])[CH3:33].[Cl:12][c:13]1[n:14][cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][c:18]1[Cl:19].[H-:10].[K+:28].[K+:29].[Na+:11].[OH2:34]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([O:9][c:13]2[n:14][cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][c:18]2[Cl:19])[cH:7][cH:8]1

Participants

9

Reactant 8

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 923Sodium ionHCID 962WaterHCID 90154-MethoxyphenolHCID 19660Carbonate IonHCID 1122342,3-Dichloro-5-(trifluoromethyl)pyridineHCID 166653Hydride

Product 1

HCID 199860193-Chloro-2-p-methoxyphenoxy-5-trifluoromethylpyridine

Sources & evidence

ORD record
ord-1f35da75d2324bf592bbd7409ea28934
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…