HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous Chloride → 1-methyl-1H-1,2,3-benzotriazol-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 1H-Benzotriazole, 1-methyl-5-nitro- | HCID 335269 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 1-methyl-1H-1,2,3-benzotriazol-5-amine | HCID 226197 | 68.7% |
Reaction Steps
1-Methyl-5-nitrobenzotriazole (0.7 g) was reduced by SnCl2 (4.0 g) at 0° C. in 5 mL of conc. HCl. The pH of the reaction mixture was adjusted to basic and the mixture was extracted with EtOAc. The product 5-amino-1-methylbenzotriazole (0.4 g) obtained after removal of the solvent was used for the next reaction without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445694B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-618aa8567c664f0697fa0b745555645a |
| Source note | uspto-grants-2013_05 |